Cover of: Modern concepts of insulin-like growth factors | International Symposium on Insulin-Like Growth Factors/Somatomedins (2nd 1991 San Francisco, Calif.)

Modern concepts of insulin-like growth factors

proceedings of the Second International Symposium on Insulin-Like Growth Factors/Somatomedins held January 12-16, 1991 in San Francisco, California
  • 748 Pages
  • 1.89 MB
  • 508 Downloads
  • English
by
Elsevier , New York
Somatomedin -- Congre
Statementedited by E. Martin Spencer.
ContributionsSpencer, E. Martin, 1929-
Classifications
LC ClassificationsQP552.S65 I578 1991
The Physical Object
Paginationxi, 748 p. :
ID Numbers
Open LibraryOL1624165M
ISBN 100444016171
LC Control Number91170147

Modern concepts of insulin-like growth factors. New York: Elsevier, © (OCoLC) Online version: International Symposium on Insulin-Like Growth Factors/Somatomedins (2nd: San Francisco, Calif.).

Details Modern concepts of insulin-like growth factors FB2

Modern concepts of insulin-like growth factors. New York: Elsevier, © (OCoLC) Material Type: Conference publication. Get this from a library. Modern concepts of insulin-like growth factors: proceedings of the Second International Symposium on Insulin-Like Growth Factors/Somatomedins held Januaryin San Francisco, California.

[E Martin Spencer;]. Read here ?book= Read Modern Concepts of Insulin-Like Growth Factors: Modern Concepts of Insulin-like Growth. The insulin-like growth factors (IGFs) are proteins with high sequence similarity to are part of a complex system that cells use to communicate with their physiologic environment.

This complex system (often referred to as the IGF "axis") consists of two cell-surface receptors (IGF1R and IGF2R), two ligands (Insulin-like growth factor 1 (IGF-1) and Insulin-like growth factor 2 (IGF.

Insulin-like growth factor (IGF), formerly called somatomedin, any of several peptide hormones that function primarily to stimulate growth but that also possess some ability to decrease blood glucose levels. IGFs were discovered when investigators began studying the effects of biological substances on cells and tissues outside the body.

The name insulin-like growth factor reflects the fact. Insulin-like Growth Factors 1 and 2 IGF1 synergizes with FSH in the induction of P arom activity in primate granulosa cells as well as with LH in the production of androgens by theca cells. – As such, IGF1 could contribute to the regulation of estradiol biosynthesis and follicular development.

Islet Cell Growth Factors (Medical Intelligence Unit (Unnumbered)) [Rohit N. Kulkarni] on *FREE* shipping on qualifying offers. This book, Islet Cell Growth Factors, provides a timely contribution to the current thinking regarding the concepts in the area of islet cell regeneration with special reference to insulin secreting beta by: 4.

As the name "insulin-like growth factor 1" implies, IGF-1 is structurally related to insulin, and is even capable of binding the insulin receptor, albeit at lower affinity than insulin. A splice variant of IGF-1 sharing an identical mature region, but with a different E domain is Aliases: IGF1, IGF-I, IGF1A, IGFI, MGF, insulin.

The insulin-like growth factors (IGF-I and IGF-II) are structurally related molecules that play essential roles in the regulation of cell survival, growth, proliferation, differentiation, and metabolism.

Author(s): Spencer,E Martin,; International Symposium on Insulin-Like Growth Factors/Somatomedins,(2nd: San Francisco, Calif.) Title(s): Modern concepts of insulin-like growth factors: proceedings of the Second International Symposium on Insulin-Like Growth Factors/Somatomedins held Januaryin San Francisco, California/ edited by E.

Martin. Insulin and insulin-like growth factors (IGFs) are well known as key regulators of energy metabolism and growth. There is now considerable evidence that these hormones and the signal transduction Author: Michael Pollak.

Insulin-like growth factors "under water": role in growth and function of fish and other poikilothermic vertebrates. In: Modern Concepts of Insulin-Like Growth Factors.

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Modern concepts of insulin-like growth factors: proceedings of the Second International Symposium on Insulin-Like Growth Factors/Somatomedins held January 12. Flyvbjerg A, Orskov H, Nyborg K, et al. Kidney IGF-I accumulation occurs in four different conditions with rapid initial kidney growth in rats.

In: Modern Concepts of Insulin-like Growth Factors. Spencer EM (ed.). Elsevier Science Publishing Co, New York, p.

– Google ScholarCited by: 5. The insulin-like growth factors (IGF-I and IGF-II) play important roles in the regulation of growth and metabolism. While the liver is the main source of circulating IGFs, their production by numerous extrahepatic tissues suggests the existence of autocrine and paracrine modes of action in addition to typical endocrine by: Insulin-like growth factor definition is - either of two polypeptides structurally similar to insulin that are secreted either during fetal development or during childhood and that mediate growth hormone activity.

Growth factors influence a variety of cell activities, including proliferation, migration, matrix synthesis, and differentiation. Many of these factors, including the fibroblast growth factors, insulin-like growth factors, and transforming growth factor betas, have been shown to affect chondrocyte metabolism and chondrogenesis [46,59,96,97].

The insulin-like growth factor (IGF) system in ubiquitous and plays a role in every tissue of the body. It is comprised of ligands, receptors and binding proteins, each with specific functions. The insulin-like growth factors (IGFs) participate in the growth and function of almost every organ in the body.1 Because of the wide range of their biologic effects and their therapeutic potential Cited by: The insulin-like growth factors (IGFs) are polypeptides with high sequence similarity to insulin.

IGFs are part of a complex system that cells use to communicate with their physiologic environment. During the past decade, the continued interest in insulin-related growth factors has been documented by a plethora of research programs and publications focused on these growth factors.

Both molecular and cellular biological techniques have improved and enabled investigators to study the properties of the growth factors in depth. Read Modern Concepts of Insulin-Like Growth Factors: Modern Concepts of Insulin-like Growth.

Covogotisa. PDF Growth Hormone and Insulin-like Growth Factor I in Human and Experimental Diabetes Free. Eemelie. Read Book Understanding Traumatic Brain Injury: Current Research and Future Directions Ebook.

Bitex. All done via insulin-like growth factors (IGFs) from the liver via somatomedins 1. Increase in lean muscle 2. Decrease fat 3. Increase long bones 4. Increase organ size and function 5.

Increased blood glucose. insulin-like growth factor: (ĭn′sə-lĭn-līk′) n. Abbr. IGF Either of two peptides that are structurally similar to insulin and are involved in the regulation of cell growth and differentiation.

Also called somatomedin. Insulin-like growth factor (IGF) is a polypeptide hormone similar to insulin. There are two types of insulin-like growth factors, IGF-1 and IGF-2, which are released upon stimulation by the growth hormone. Insulin-like growth factor binds to the IGF-1 or the IGF-2 receptor and the insulin receptor, and promotes growth and development.

Insulin-like growth factor-1 (IGF-1) is a hormone that, along with growth hormone (GH), helps promote normal bone and tissue growth and test measures the amount of IGF-1 in the blood. IGF-1 is produced by the liver and skeletal muscle as well as many other tissues in.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. Phone Overview. The insulin-like growth factors (IGFs) are polypeptides with high sequence similarity to are part of a complex system that cells use to communicate with their physiologic environment.

This complex system (often referred to as the IGF "axis") consists of two cell-surface receptors (IGF1R and IGF2R), two. Nutritional regulation of IGF-I and postnatal growth Primary tabs.

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view (active tab) "Modern concepts of Insulin-like Growth Factors" (ISBN: ) Publisher: EM Spencer, Modern concepts of Insulin-like Growth Factors, Elsevier: New York Cited by: 6.

Molecular characterization and expression analysis of insulin-like growth factor-1 and insulin-like growth factor binding protein-1 genes in Qinghai-Tibet plateau Bos grunniens and lowland Bos taurus Johnson et al., "Polymorphisms and circulating levels in the insulin-like growth factor system and risk of breast cancer: a systematic review.

Annual Review of Nutrition Insulin-Like Signaling, Nutrient Homeostasis, and Life Span Akiko Taguchi and Morris F. White Annual Review of Physiology Control of Growth by the Somatropic Axis: Growth Hormone and the Insulin-Like Growth Factors Have Related and Independent Roles Andrew A. Butler and Derek Le Roith Annual Review of PhysiologyCited by:.

Clemmons DR. Clinical utility of measurements of insulin-like growth factor 1. Nat Clin Pract Endocrinol Metab ; Butler AA, Le Roith D. Control of growth by the somatropic axis: growth hormone and the insulin-like growth factors have related and independent roles.

Annu Rev Physiol ; The effects of insulin-like growth factor I on renal hemodynamics. In: E. Martin Spencer (Editor), Modern Concepts of Insulin-like Growth Factors. Elsevier, New York, 6) Kopple J, G Brunori, M Leiserowitz, C Mattimore, R Hirschberg: Growth hormone treatment for patients with renal failure.insulin-like growth factor (IGF) Any of certain polypeptides (see growth factor) that are structurally similar to the hormone insulin and promote division and growth of are two principal types: IGF-I (somatomedin C) and IGF-II (somatomedin A).Growth hormone stimulates the liver to release IGF-I, which circulates in the bloodstream bound to several specific IGF-binding proteins.